COLLAGEN The protein of youth.

What it is and where it is

Collagen is the most abundant protein in the human body, it is composed of amino acids and accounts for approximately 30% of the total protein content. It holds all living tissues together and ensures the integrity, elasticity and regeneration of the skin, cartilage and bones.

Distribution of collagen in the body
Tendons 85%
Skin 75%
Ligaments 70%
Joint cartilages 70%

Where is it?
Collagen is a natural, safe ingredient and can be found in foods such as bone and skin broth.

Collagen peptides
With the help of enzymes, the controlled breakdown of native collagen produces collagen peptides, small and easy to digest.

When do we start
to lose collagen?

The production of collagen in our body reaches its maximum level around the age of 20 and as we age the metabolic cycle of collagen begins to slow down causing a gradual deterioration of collagen fibers and all connective tissues. This deterioration process will affect different parts of our body, for example the skin, as illustrated in the following image.

The loss of collagen is a natural process, but other factors such as exposure to UV rays, pollution and lifestyle can cause premature or more intense signs of aging.

Digestibility and composition of peptides

Digestibility and bioavailability
The highly bioavailable hydrolyzed collagen is digested and absorbed within a few hours of ingestion.
This fast availability ensures the effective delivery of essential peptides and amino acids to the appropriate parts of the body.

The composition of collagen peptides
Like the starting collagen protein, peptides are characterized by high levels of the amino acids glycine, proline and hydroxyproline, which together account for approximately 50% of the total. Hydroxyproline is found only in collagen and forms stable bonds with other amino acids. The resulting peptides have unique bioactive properties.
Collagen peptides can act as messengers, triggering the synthesis and reorganization of new collagen fibers which will then compose the structure of the skin tissues.

Specific amino acids such as hydroxyproline contained in the absorbed collagen peptides can act as messengers to activate fibroblastic cells.

The effects of collagen

Collagen makes up 75% of the dry mass of the skin and collagen fibers provide the infrastructure for elastin, which maintains skin elasticity and firmness.

Since, with the passage of age, the degradation of collagen prevails over its production, our skin dehydrates and becomes thinner and the signs of aging begin to appear.

The effects of collagen on skin elasticity and wrinkles around the eyes
Clinical studies have shown that the consumption of collagen peptides effectively improves the skin structure making it more elastic with consequent reduction of wrinkles.
Below are references to two clinical studies.

CLINICAL STUDY – Proksch et al. 2013a (source: PubMed)

CLINICAL STUDY – Proksch et al. 2013b (source: PubMed)

Benefits for hair and nails

Other benefits of collagen peptides: hair and nails
Collagen is the structural basis of skin and nails. The amino acids of the collagen peptides are ingested, absorbed and used by the hair follicles to produce keratin, a protein necessary for healthy hair.
The fingernails and toenails are also made up of keratin and sit on top of a layer of dermis.

CLINICAL STUDY – DOI: 10.1111/jocd.12393 (Source: PubMed)

CLINICAL STUDY – DOI 10.17470/NF-020-0019 (source: PubMed)

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